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Nonapeptide-1 – The Melanin “Switch” Blocker (Melanostatine-5)

  • Nonapeptide-1
  • CAS number: 158563-45-2
  • Molecular weight: 1206.5 g/mol
  • Molecular formula: C61H87N15O9S
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water

    【Product Overview】

    We are a specialized global supplier of Nonapeptide-1, a powerful biomimetic peptide famously known by the trade reference Melanostatine-5. This peptide acts as a specific antagonist to the α-MSH (Melanocyte-Stimulating Hormone). Unlike traditional whiteners that kill cells or irritate the skin, Nonapeptide-1 simply "blocks the signal" that tells the skin to produce melanin. We provide high-purity, cosmetic-grade powder to formulators creating safe, non-irritating brightening serums and spot-correcting treatments.

    【Key Advantages】

    The MSH Antagonist (The "Off" Switch): Pigmentation starts when MSH binds to the MC1-R receptor on melanocytes. Nonapeptide-1 competes for this receptor, effectively preventing the activation of Tyrosinase before it even begins. It stops melanin synthesis at the very source.

    Safe Whitening Alternative: Unlike Hydroquinone (cytotoxic) or Kojic Acid (irritating), Nonapeptide-1 does not interfere with cell viability. It is safe for long-term use and ideal for sensitive skin whitening lines.

    Targeted Spot Correction: By inhibiting the pathway triggered by UV damage and inflammation, it is highly effective at reducing Hyperpigmentation and reducing the contrast of dark spots against the surrounding skin.

    Even Skin Tone: Clinical data suggests a significant reduction in melanin synthesis, leading to a brighter, more uniform complexion without the risk of "Halo Spots" (hypopigmentation).

    【Logistics & Service】

    Cosmetic Grade Quality: Manufactured under strict cGMP guidelines for cosmetic ingredients, ensuring high purity and absence of heavy metals.

    Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation for your regulatory files.

    Formulation Stability: Excellent stability in aqueous solutions. It works best in a pH range of 4.0 – 8.0.

    Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.

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