Fluoxetine Hydrochloride is the hydrochloride salt form of fluoxetine, which enhances its solubility and stability.
Fluoxetine is a new generation, potent selective serotonin reuptake inhibitor (SSRI). It is used to treat depression with efficacy comparable to tricyclics.
It is a selective serotonin reuptake inhibitor (SSRI) and is commonly used as a raw material in the production of antidepressants. The finished product is typically in the form of capsules or tablets.
| Analysis | Specification |
| Description | White to off-white Crystalline Powder |
| Solubility | Sparingly soluble in water and in dichloromethane, freely soluble in alcohol and in methanol.Practically insoluble in ether. |
| Identification: A: B: | By infra-red absorption spectrum Gives the reactions ofchlorides, |
| Water | Not More than 0.5 % |
| Heavy Metals | Not more than 0.003 % |
| Sulphated Ash | Not more than 0.1% |
| Related Compound | Total impurities NMT 0.5 % |
| Organic Volatile Impurity | To Comply the test |
| Assay | Fluoxetine Hydrochloride contains not less than 98.0% and not more than 102.0 % of:C17H18F3NO,HCl, calculated on the anhydrous basis. |
Fluoxetine Hydrochloride can effectively inhibit neurons from taking up 5-hydroxytryptamine from the synaptic cleft, increase the level of serotonin in the cleft, and thus improve mood and mental disorders.
1.For Major Depressive Disorder (MDD).
2.For Obsessive-Compulsive Disorder (OCD).
3.For Panic Disorder.
4.For Bulimia Nervosa.
5.For Premenstrual Dysphoric Disorder (PMDD).
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