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Fluoxetine Hydrochloride

  • CAS number: 56296-78-7
  • Molecular formula: C₁ₐH₁₉ClF₃NO
  • Molecular weight: 345.79
  • Appearance: White Powder
  • Specification: 98%

    Feature

    Fluoxetine Hydrochloride is the hydrochloride salt form of fluoxetine, which enhances its solubility and stability.
    Fluoxetine is a new generation, potent selective serotonin reuptake inhibitor (SSRI). It is used to treat depression with efficacy comparable to tricyclics.
    It is a selective serotonin reuptake inhibitor (SSRI) and is commonly used as a raw material in the production of antidepressants. The finished product is typically in the form of capsules or tablets.

    Specification-COA

    AnalysisSpecification
    DescriptionWhite to off-white Crystalline Powder
    Solubility
    Sparingly soluble in water and in dichloromethane, freely soluble in alcohol and in methanol.Practically insoluble in ether.
    Identification:
    A:
    B:

    By infra-red absorption spectrum
    Gives the reactions ofchlorides,
    WaterNot More than 0.5 %
    Heavy MetalsNot more than 0.003 %
    Sulphated AshNot more than 0.1%
    Related CompoundTotal impurities NMT 0.5 %
    Organic Volatile ImpurityTo Comply the test
    AssayFluoxetine Hydrochloride contains not less than 98.0% and not more than 102.0 % of:C17H18F3NO,HCl, calculated on the anhydrous basis.

    Function and Application

    Fluoxetine Hydrochloride can effectively inhibit neurons from taking up 5-hydroxytryptamine from the synaptic cleft, increase the level of serotonin in the cleft, and thus improve mood and mental disorders.

    1.For Major Depressive Disorder (MDD).
    2.For Obsessive-Compulsive Disorder (OCD).
    3.For Panic Disorder.
    4.For Bulimia Nervosa.
    5.For Premenstrual Dysphoric Disorder (PMDD).

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