Dioscorea is an important raw material for synthetic hormone medicine. It is mainly exist in the rhizomes of Dioscorea zingiberensis, and its structure contains a variety of steroidal saponin ligands. It appears as a white, slightly yellow crystalline powder and is an important intermediate and basic raw material for synthetic hormones.
Diosgenin is fermented to remove the sugar group and converted into diosgenin, which has anti-inflammatory effects, lowers cholesterol, and improves the ability to secrete serum antibody IgG.
Items | Standard | Results | |
Appearance | Light yellow or almost white crystalline powder,odorless | Complies | |
Clarity | Should be clanified in 1% ethanol solution | Complies | |
Melting Point | ≥190℃ | 195℃-204.5℃ | |
Specific Rotation | +120°~+122° | Complies | |
Loss on Drying | ≤0.5% | 0.20% | |
Assay | ≥95.0%(HPLC) | 98.08% | |
Particle Size | 100%<16Mesh | 100%<16Mesh 83.2%<20Mesh | |
Other impurities | Should not be detected | Complies | |
Sapogenins in Diosgenin | Should be in accordance with Sigma Standard Diosgenin | Complies | |
Conclusion | The items tested conform to the requirements of enterprise standard. |
1.Diosgenin wild yam has anti-inflammatory, anti-infective, anti-allergic, anti-viral and anti-shock pharmacological effects.
2.It has lipid-lowering and cholesterol metabolism regulating pharmacological activity.
This substance can protect endothelial function,so it is an important drug for the treatment of rheumatism and cardiovascular diseases.
3.It has estrogenic activity.
4.Diosgenin powder can lower serum cholesterol levels and is a special regulator of cholesterol metabolism. It can indirectly promote cholesterol transporters.
5.Relieve non-alcoholic fatty liver disease. Dioscin protects the body from non-alcoholic fatty liver disease (NAFLD) by regulating metabolic disorders and lipid metabolism.
1.Pharmaceutical intermediate and raw material. It is an important basic raw material for the production of dexamethasone, hydrocortisone, norethindrone and other steroid drugs.
2.For research.
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