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Cycloastragenol Powder

  • Plant Latin name: Astragalus root
  • Used part: Root
  • CAS No: 78574-94-4
  • Cycloastragenol≥10.00%
  • Custom Service Available

    Feature

    Cycloastragenol, extracted from the medicinal plant Astragalus membranaceus, is a triterpenoid with diverse pharmacological effects.
    Cycloastragenol Powder is primarily derived from the hydrolysis of astragaloside IV. It has a small molecular weight, good lipophilicity, and excellent bioavailability.
    Its biological activities include anti-aging, anti-fibrosis, immunomodulation, telomerase activation, and anti-Alzheimer's disease.

    Manufacturing Flow chart:

    Raw Material→QC Identification→Cleaning→Pulverization→Water Extraction→Filtration→Resin adsorption→Ethanol washing→Membrane separation→
    Concentrating ethanol→Filtration→Recrystallization→Astragaloside IV→Hydrolysis→
    Cycloastragenol crude products→Recrystallization→Cycloastragenol 98%

    Specification-COA

    ItemSpecificationResultMethod
    Maker Compounds Cycloastragenol≥10.00%10.27%HPLC-RID 
    Organoleptic   
    AppearanceBrown-yellow powderConformsVisual
    OdorCharacteristicConformsOrganoleptic
    TasteCharacteristicConformsOrganoleptic
    Physical Characteristics   
    Particle Size100%Through 80 meshConformsGB5507-85
    Loss on Drying≤5.00%3.29%CP2020
    Ash content≤0.50%0.1%CP2020
    Residual Solvent<0.1%Confirms GC-MS
    Pesticide ResidueNegativeConfirmsGB/T5009-19-199
    Heavy metals   
    Total Heavy Metals≤5ppmConformsAtomic Absorption
    As≤0.5ppm0.0042ppmAtomic Absorption
    Pb≤0.5ppm0.0093ppmAtomic Absorption
    Hg≤0.5 ppm0.002ppmAtomic Absorption
    Cd≤0.5ppm0.002ppmAtomic Absorption
    Microbiological Tests   
    Total bacteria count≤1000cfu/gConformsAOAC
    Yeast & Moulds≤100cfu/gConformsAOAC
    E.ColiNegativeNegativeAOAC
    SalmonellaNegativeNegativeAOAC
    Pseudomonas aeruginosaNegativeNegativeAOAC
    EnterobacteriaceaeNegativeNegativeAOAC
    Staphylococcus aureusNegativeNegativeAOAC
    Conclusion:Conforms

    What does cycloastragenol do?

    1. Anti-aging effects, potentially treating telomere dysfunction. Cycloastragenol (CAG) is a natural telomerase activator that increases telomerase activity, thereby slowing telomere shortening and exhibiting anti-aging and anti-apoptotic effects.
    2. Antioxidant properties. It can improve or regulate the metabolism of senescent cells, enhance cell lifespan, and promote cell proliferation.
    3. Anti-fibrosis. Cycloastragenol (CAG) has ameliorative effects on fibrosis.

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