Cycloastragenol, extracted from the medicinal plant Astragalus membranaceus, is a triterpenoid with diverse pharmacological effects.
Cycloastragenol Powder is primarily derived from the hydrolysis of astragaloside IV. It has a small molecular weight, good lipophilicity, and excellent bioavailability.
Its biological activities include anti-aging, anti-fibrosis, immunomodulation, telomerase activation, and anti-Alzheimer's disease.
Manufacturing Flow chart:
Raw Material→QC Identification→Cleaning→Pulverization→Water Extraction→Filtration→Resin adsorption→Ethanol washing→Membrane separation→
Concentrating ethanol→Filtration→Recrystallization→Astragaloside IV→Hydrolysis→
Cycloastragenol crude products→Recrystallization→Cycloastragenol 98%
Item | Specification | Result | Method |
Maker Compounds | Cycloastragenol≥10.00% | 10.27% | HPLC-RID |
Organoleptic | |||
Appearance | Brown-yellow powder | Conforms | Visual |
Odor | Characteristic | Conforms | Organoleptic |
Taste | Characteristic | Conforms | Organoleptic |
Physical Characteristics | |||
Particle Size | 100%Through 80 mesh | Conforms | GB5507-85 |
Loss on Drying | ≤5.00% | 3.29% | CP2020 |
Ash content | ≤0.50% | 0.1% | CP2020 |
Residual Solvent | <0.1% | Confirms | GC-MS |
Pesticide Residue | Negative | Confirms | GB/T5009-19-199 |
Heavy metals | |||
Total Heavy Metals | ≤5ppm | Conforms | Atomic Absorption |
As | ≤0.5ppm | 0.0042ppm | Atomic Absorption |
Pb | ≤0.5ppm | 0.0093ppm | Atomic Absorption |
Hg | ≤0.5 ppm | 0.002ppm | Atomic Absorption |
Cd | ≤0.5ppm | 0.002ppm | Atomic Absorption |
Microbiological Tests | |||
Total bacteria count | ≤1000cfu/g | Conforms | AOAC |
Yeast & Moulds | ≤100cfu/g | Conforms | AOAC |
E.Coli | Negative | Negative | AOAC |
Salmonella | Negative | Negative | AOAC |
Pseudomonas aeruginosa | Negative | Negative | AOAC |
Enterobacteriaceae | Negative | Negative | AOAC |
Staphylococcus aureus | Negative | Negative | AOAC |
Conclusion: | Conforms |
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