Cycloastragenol, extracted from the medicinal plant Astragalus membranaceus, is a triterpenoid with diverse pharmacological effects.
Cycloastragenol Powder is primarily derived from the hydrolysis of astragaloside IV. It has a small molecular weight, good lipophilicity, and excellent bioavailability.
Its biological activities include anti-aging, anti-fibrosis, immunomodulation, telomerase activation, and anti-Alzheimer's disease.
Manufacturing Flow chart:
Raw Material→QC Identification→Cleaning→Pulverization→Water Extraction→Filtration→Resin adsorption→Ethanol washing→Membrane separation→
Concentrating ethanol→Filtration→Recrystallization→Astragaloside IV→Hydrolysis→
Cycloastragenol crude products→Recrystallization→Cycloastragenol 98%
| Item | Specification | Result | Method |
| Maker Compounds | Cycloastragenol≥10.00% | 10.27% | HPLC-RID |
| Organoleptic | |||
| Appearance | Brown-yellow powder | Conforms | Visual |
| Odor | Characteristic | Conforms | Organoleptic |
| Taste | Characteristic | Conforms | Organoleptic |
| Physical Characteristics | |||
| Particle Size | 100%Through 80 mesh | Conforms | GB5507-85 |
| Loss on Drying | ≤5.00% | 3.29% | CP2020 |
| Ash content | ≤0.50% | 0.1% | CP2020 |
| Residual Solvent | <0.1% | Confirms | GC-MS |
| Pesticide Residue | Negative | Confirms | GB/T5009-19-199 |
| Heavy metals | |||
| Total Heavy Metals | ≤5ppm | Conforms | Atomic Absorption |
| As | ≤0.5ppm | 0.0042ppm | Atomic Absorption |
| Pb | ≤0.5ppm | 0.0093ppm | Atomic Absorption |
| Hg | ≤0.5 ppm | 0.002ppm | Atomic Absorption |
| Cd | ≤0.5ppm | 0.002ppm | Atomic Absorption |
| Microbiological Tests | |||
| Total bacteria count | ≤1000cfu/g | Conforms | AOAC |
| Yeast & Moulds | ≤100cfu/g | Conforms | AOAC |
| E.Coli | Negative | Negative | AOAC |
| Salmonella | Negative | Negative | AOAC |
| Pseudomonas aeruginosa | Negative | Negative | AOAC |
| Enterobacteriaceae | Negative | Negative | AOAC |
| Staphylococcus aureus | Negative | Negative | AOAC |
| Conclusion: | Conforms | ||
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