Albendazole is an organic compound discovered in 1972. As a broad-spectrum anthelmintic, an imidazole derivative, it is a fundamental health remedy. It possesses excellent insecticide activity, low toxicity, and safety. It significantly inhibits nematodes, tapeworms, and egg development.
Albendazole is a white or off-white powder, odorless. It is insoluble in water, nearly insoluble in ethanol, and soluble in glacial acetic acid.
| Tests | Results | Specifications |
| Description | White to off-white crystalline powder | Off-white crystalline powder |
| Ref Standard | USP | USP |
| Identification | Infrared spectrum should be consistent with the reference map | Complies |
| Total impurities≤0.5% | 0.12% | |
| Related compounds | Any single impurity ≤0.5% | Max single impurity 0.10% |
| Total impurities≤0.5% | 0.12% | |
| Loss on drying | ≤0.5% | 0.11% |
| Residual | ≤0.5% | 0.11% |
| Iron salts | Should comply with the standard | Complies |
| Melting Point | 206-212℃ | 209℃ |
| Purity | 98.5%, On anhydrous basis（C21H25ClN2O4S） | 99.5% |
| Conclusion： Conforms to in-house Standards | ||
Albendazole is a highly effective, broad-spectrum anthelmintic that can also be used to prevent parasitic infections, but it is ineffective against insects.Its mechanism of action is by inhibiting glucose absorption, leading to glycogen depletion in the insect body.
Also, it inhibits the fumarate reductase system, hindering ATP production.
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