Feature

Here are some of the peptide products for weight loss now on the market or in advanced phases of development (mostly GLP-1 receptor agonists and related peptides).The American College of Cardiology (ACC) points out that nutrient-stimulating hormone (NuSH) therapy, including liraglutide, semaglutide and telpotide, is the most effective weight loss drug currently available.

1. Semaglutide
   Type: GLP-1 receptor agonist
   Status: FDA-approved
   Effect:
   For weight loss and type 2 diabetes.
   Up to ~15% body weight loss in clinical trials.
   Reduces appetite and improves blood glucose.
2. Tirzepatide
   Type: Dual agonist (GLP-1 + GIP)
   Status: FDA-approved
   Effect:
   For weight loss and type 2 diabetes.
   ~20–22% weight loss in clinical studies.
   Better metabolic improvements than semaglutide.
3. Retatrutide
   Type: Triple agonist (GLP-1 + GIP + glucagon)
   Status: Phase 3 clinical trials (as of 2024)
   Effect:
   Up to 24% weight loss in trials