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Tetrapeptide-30 – The Anti-Inflammatory Brightener (Pep 4-Even)

  • Tetrapeptide-30
  • Sequence: Pro-Lys-Glu-Lys (PKEK)
  • Molecular weight: 499.56 g/mol
  • Molecular formula: C22H37N5O8
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water

    【Product Overview】 We are a specialized global supplier of Tetrapeptide-30, a highly intelligent skin-brightening peptide famously known by the trade reference TEGO® Pep 4-Even. Unlike traditional whitening agents that cytotoxicity kill melanocytes, Tetrapeptide-30 works via a dual mechanism: it inhibits the Tyrosinase activation pathway while simultaneously suppressing the inflammatory cytokines (IL-6, IL-8) that trigger pigmentation. We provide high-purity, cosmetic-grade powder to formulators developing treatments for Post-Inflammatory Hyperpigmentation (PIH), acne marks, and age spots.

    【Key Advantages】

    Targeting PIH (Acne Marks): Its standout feature is treating Post-Inflammatory Hyperpigmentation. By reducing the skin's inflammatory response to UV and acne, it prevents the formation of dark spots left behind by breakouts. It is the "Smart Choice" for acne-prone skin lines.

    Dual-Action Mechanism:

    Anti-Inflammatory: Significantly reduces the expression of key inflammatory mediators (Interleukins).

    Melanin Inhibition: Downregulates the expression of the POMC gene (the precursor to MSH) and inhibits the activation of Tyrosinase.

    Safe for Ethnic Skin: Many whitening agents are too harsh for darker skin tones (Fitzpatrick IV-VI). Tetrapeptide-30 is non-irritating and uniquely effective on ethnic skin, reducing the contrast between hyperpigmented spots and normal skin.

    Excellent Stability: Unlike Vitamin C or Kojic Acid, Tetrapeptide-30 is chemically stable, compatible with glycolic acid, and does not oxidize or change color in formulations.

    【Logistics & Service】

    Cosmetic Grade Quality: Manufactured under strict cGMP guidelines for cosmetic ingredients, ensuring high purity and safety.

    Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation.

    Formulation Advice: This peptide is robust. It can be added to the water phase and withstands temperatures up to 40°C. Ideal for pairing with Niacinamide for a synergistic brightening effect.

    Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.

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