【Product Overview】 We are a specialized global supplier of Oligopeptide-68, a sophisticated biomimetic peptide famously known by the trade reference Beta-White. This peptide represents a breakthrough in skin brightening technology by mimicking the action of TGF-β (Transforming Growth Factor beta). Instead of merely inhibiting Tyrosinase, Oligopeptide-68 binds to the TGF-β receptor to inhibit the MITF pathway—the master transcriptional regulator of all pigmentation enzymes. We provide high-purity powder to formulators creating high-performance whitening creams, spot correctors, and "porcelain skin" treatments.
【Key Advantages】
MITF Pathway Inhibition (The Master Switch): Most whitening agents only stop Tyrosinase. Oligopeptide-68 goes upstream to inhibit MITF (Microphthalmia-associated Transcription Factor). By downregulating MITF, it simultaneously reduces the production of Tyrosinase, TRP-1, and TRP-2. It shuts down the entire pigment production factory, not just one machine.
Constitutive & Facultative Pigmentation: It is unique in its ability to reduce both Constitutive Pigmentation (your natural skin color baseline) and Facultative Pigmentation (tanning caused by UV exposure). This makes it ideal for overall skin lightening and brightening.
Time-Release Potential: Due to its complex structure, it is frequently formulated in liposomal vehicles (lecithin-based) by manufacturers to enhance penetration and stability, allowing for deep delivery into the basal layer where melanocytes reside.
Superior Efficacy: Clinical comparisons often show it outperforming Arbutin and Vitamin C in reducing the appearance of age spots and dyschromia over a 4-week period.
【Technical Specifications】
INCI Name: Oligopeptide-68
Common Trade Ref: Beta-White
CAS Number: 1206525-47-4
Sequence: Arg-Asp-Gly-Gln-Ile-Leu-Ser-Thr-Trp-Tyr (RDGQILSTWY)
Mechanism: TGF-β Agonist / MITF Pathway Inhibitor
Molecular Formula: C62H91N17O18
Molecular Weight: 1374.5 g/mol
Appearance: White to off-white powder
Purity: ≥98.0% (HPLC)
Solubility: Soluble in water (Best dispersed with lecithin/liposomes).
Recommended Dosage: 1.0% – 5.0% (of a solution) or 10-50ppm (powder).
【Logistics & Service】
Cosmetic Grade Quality: Manufactured under strict cGMP guidelines for cosmetic ingredients, ensuring high purity and safety.
Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation for your regulatory files.
Formulation Advice: We recommend encapsulating this peptide (or using a pre-encapsulated form) for maximum stability and efficacy. Add to the formulation below 40°C.
Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.
Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and…
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