Melittin is the main active ingredient in bee venom, accounting for about 40-60% of its dry weight. It is a short-chain amphipathic peptide composed of 26 amino acids, and its secondary structure is an alpha helical structure.
This substance has good biological activity and has hydrophobic and hydrophilic regions, which enable it to enter and destroy cell membranes.
Melittin is the cause of pain and inflammation caused by bee stings. In addition, it also has some potential pharmacological properties.
Items | Specifications | Results |
Protein | Not less than 98% | 98.7% |
Loss on drying | Not more than 3% | 2.52% |
Water insoluble substances | Not more than 4% | conform |
total ash | Not more than 2% | 1.27% |
Activity of phospholipase A2 IU/mg | Not less than 30% | 34% |
Haemolysis | Not more than 20mg/ml | 18.9mg/ml |
PH | 4.5-6.5 | 5.3 |
Melittin | Not less than 40% | 54.8% |
Conclusion: in conformity with the enterprise standard |
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