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Hexapeptide-10 – The Dermal-Epidermal Junction (DEJ) Restorer

  • Hexapeptide-10
  • CAS number: 146439-94-3
  • Molecular weight: 659.79 g/mol
  • Molecular formula: C28H53N9O9
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water

    【Product Overview】

    We are a specialized global supplier of Hexapeptide-10, a bioactive firming peptide famously known by the trade reference Serilesine. This synthetic hexapeptide is designed to mimic the adhesion sequence of Laminin-1. Its primary function is to restructure and strengthen the Dermal-Epidermal Junction (DEJ), the critical interface that bonds the skin layers together. We provide high-purity, cosmetic-grade powder to formulators developing "Redensifying" and "Anti-Sagging" products for both face and body.

    【Key Advantages】

    DEJ Reinforcement (The "Double-Layer" Effect): As skin ages, the junction between the dermis and epidermis flattens, causing skin to become loose and fragile. Hexapeptide-10 boosts the synthesis of Laminin-5, α6-Integrin, and Hemidesmosomes. This effectively "glues" the two layers back together, restoring the skin's structural integrity.

    Laminin-1 Mimic: By mimicking the specific cell-adhesion sequence (SIKVAV) of Laminin, it promotes cell proliferation and migration, leading to a thicker, more compact epidermis.

    Anti-Sagging & Redensifying: Clinical data supports its ability to significantly increase skin density and compactness. It is an ideal ingredient for formulations targeting mature skin, post-weight loss firming, and neck/décolleté care.

    High Bioactivity: It targets the structural collapse of the skin at the cellular level, offering a visible improvement in skin smoothness and elasticity.

    【Logistics & Service】

    Cosmetic Grade Quality: Manufactured under strict GMP guidelines for cosmetic ingredients, ensuring low bio-burden and absence of heavy metals.

    Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation for your regulatory files.

    Application Support: We can provide guidance on formulation compatibility. Hexapeptide-10 is stable in aqueous solutions and compatible with most cosmetic thickeners.Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.

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