Coenzyme A is the main carrier of activated acyl groups in cells. Its structure consists of pantothenic acid (vitamin B5), adenosine diphosphate (ADP) and a thiol (-SH) group at one end.
As an important coenzyme, it plays a central role in metabolism.
Inspection Items | Specification | Results |
Description | It should be white or yellowish powder; it smells like garlic;it is hygroscopic | Conform |
Ultraviolet spectra | There should be maximum absorption at the wavelength of 258nm; There should be maximum absorption at the wavelength of 230nm. | Conform |
Clarity and color of solution | Should comply with the regulations | Conform |
Uniformity | Should comply with the regulations | Conform |
benzene | <0.0002% | not detected |
epichlorohydrin | ≤0.006% | not detected |
Loss on drying | ≤5.0% | 3.80% |
Related substances | <15.0% | 8.60% |
Bacterial endotoxin | The amount of endotoxin per unit of Coenzyme A should be less than 0.25EU | Conform |
Valence determination | The titer of coenzyme A per 1mg should not be less than 250 pieces | 330U/mg |
Total aerobic bacteria | ≤1000 cfu/g | <10 cfu/g |
Total number of molds and yeasts | ≤100 cfu/g | <10 cfu/g |
Escherichia coli | Should not be detected/1g | Not detected/g |
Conclusion | Conformed standard |
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