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Artemisinin

  • CAS No.: 63968-64-9
  • Active ingredient: Artemisinin
  • Specs: 98%
  • Appearance: White crystal powder
  • Custom capsule available
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                            Feature

                            Artemisinin is extracted from the leaves of Artemisia annua and is a sesquiterpene lactone compound containing a peroxide bridge structure. It is a natural compound with antimalarial properties, with the advantages of rapid onset and low toxicity.
                            Currently, the industrial methods for obtaining artemisinin are mainly extraction, separation, and purification.
                            Artemisinin powder is almost insoluble in water, but soluble in organic solvents such as ethanol and ether.

                            Specification-COA

                            ItemsSpecificationsResults
                            SolubilityIt is easily soluble in acetone, ethyl acetate, chloroform, soluble in methanol, ethanol, ethanol, ether and petroleum ether, almost insoluble in water, and easily soluble in glacial acetic acid.Conforms
                            AppearanceColorless needle-shaped crystals, bitter tasteConforms
                            Melting point150-153℃150.9-151.8℃
                            Specific rotation+75℃—78°76.9°
                            Identification
                            Color reaction 1The solution should appear redConforms
                            Color reaction 2The solution should be dark purpleConforms
                            HPLCThe retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution.Conforms
                            IRhe infrared absorption spectrum of this product should be consistent with that of the reference product (spectral set 220).Conforms
                            Detection
                            Related substances (Thin layer chromatography)If the test solution shows spots, the depth is the same as that of the control solution.Conforms
                            Loss on drying≤0.5%0.15%
                            Ignition residue≤0.1%0.05%
                            Content (dry product)98.0%—102.0%（HPLC）99.30%
                            Other tests
                            Related substances (HPLC)Total impurities≤5.0%2.26%
                            Single impurity≤3.0%1.99%
                            ClarityShould be less than level 1Conforms

                            What is artemisinin mainly used for?

                            1. The most famous pharmacological effect of artemisinin and its derivatives is anti-malarial. WHO recommends the use of artemisinin drugs such as artesunate and artemether to treat malaria. The metabolite of artemisinin and its two derivatives is dihydroartemisinin, which is also an effective antimalarial drug ingredient.
                            2. In addition, it also has anti-inflammatory, antifungal, and anti-fibrosis effects.
                            3. Artemisinin improves polycystic ovary syndrome by mediating LONP1-CYP11A1 interaction.

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