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Somatostatin Acetate (SRIF-14) – Native Hormone API

  • ASomatostatin Acetate (SRIF-14)
  • CAS number: 38916-34-6
  • Molecular weight: 1637.9 g/mol
  • Molecular formula: C76H104N18O19S2
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water and 1% acetic acid

    【Product Overview】 We are a premier global supplier of Somatostatin Acetate, the synthetic form of the naturally occurring 14-amino acid peptide, also known as Growth Hormone-Inhibiting Hormone (GHIH) or SRIF-14. While synthetic analogues (like Octreotide) are used for long-term therapy, native Somatostatin remains the indispensable Reference Standard for physiological research and the active ingredient for acute clinical formulations (e.g., Stilamin® generics) used to control acute gastrointestinal bleeding. We provide high-purity, synthetic Somatostatin to pharmaceutical manufacturers and research institutions worldwide.

    【Key Advantages】

    The Biological Benchmark: As the native ligand for all five somatostatin receptor subtypes (sst1–sst5), this peptide is the absolute baseline control for binding affinity assays. It is essential for researchers comparing the efficacy of novel analogues.

    Rapid On/Off Profile: Unlike its long-acting cousins, native Somatostatin has a very short half-life (1–3 minutes). This characteristic is highly valued in acute care research, allowing for precise, minute-by-minute titration of the inhibitory effect via continuous infusion.

    Broad Inhibitory Spectrum: It exhibits potent inhibitory effects on a wide range of physiological functions, including the release of Growth Hormone (GH), TSH, Insulin, Glucagon, and Gastrin, making it a versatile tool for endocrinology and gastroenterology studies.

    Synthetic Purity: Our product is produced via advanced solid-phase peptide synthesis (SPPS), ensuring a ≥98.0% purity (HPLC). This eliminates the immunogenic risks and batch variability associated with older extraction-based methods.

    【Technical Specifications】

    Chemical Name: Somatostatin; Somatostatin-14; SRIF-14

    CAS Number: 38916-34-6

    Sequence: Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Cyclic disulfide bridge: 3-14)

    Mechanism: Pan-Somatostatin Receptor Agonist

    Molecular Formula: C76H104N18O19S2

    Molecular Weight: 1637.9 g/mol

    Appearance: White to off-white lyophilized powder

    Solubility: Soluble in water and 1% acetic acid.

    Storage: Store at -20°C. Protect from light.

    【Logistics & Service】

    Cold Chain Logistics: Somatostatin is sensitive to enzymatic degradation. We ship strictly using validated thermal packaging (VIP box + dry ice/gel packs) to ensure the peptide remains intact during global transit.

    Global Export: We are experienced in shipping biochemicals globally. We provide full HS Code support (typically 2937.19) and non-clinical use declarations to facilitate smooth customs clearance.

    Documentation: Comprehensive COA, Mass Spectrometry (MS), and HPLC Chromatograms are provided to validate identity and purity.

    Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical injection, or patient administration without regulatory approval.

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