【Product Overview】 We are a specialized global supplier of Pramlintide Acetate, a synthetic polypeptide analogue of human amylin (islet amyloid polypeptide). Unlike native amylin, which is prone to aggregation and insolubility, Pramlintide is engineered with three proline substitutions to ensure stability and bio-availability. It is a critical API for research into glucose control, specifically as an adjunct therapy for Type 1 and Type 2 diabetes to manage postprandial blood sugar levels and gastric emptying.

【Key Advantages】

Structural Stability: Native human amylin is notoriously unstable and forms amyloid fibrils. Our Pramlintide features specific Proline substitutions (at positions 25, 28, and 29), which prevent aggregation while retaining full biological activity. This makes it a reliable reagent for solution-based assays.

Synergistic Research: Pramlintide is currently a hot topic in "Combination Therapy" research. It is frequently studied alongside Insulin or GLP-1 agonists (like Semaglutide) to investigate synergistic effects on weight loss and satiety.

High Purity Assurance: We guarantee ≥98.0% purity (HPLC). Our synthesis process strictly maintains the integrity of the essential Cys2-Cys7 disulfide bridge, which is vital for receptor binding affinity.

Scalable Supply: We support the entire development lifecycle, from milligram-level pre-clinical trials to bulk gram-level supply for generic formulation development.

【Logistics & Service】

Cold Chain Logistics: We utilize validated thermal packaging (VIP box + gel packs) to ensure the peptide remains within the optimal temperature range during global transit.

Regulatory Support: We are experienced in shipping metabolic APIs globally. We provide full HS Code support (typically 2937.19) and non-clinical declarations to facilitate smooth customs clearance to the US, EU, and Asia.

Analytical Data: Comprehensive documentation, including H-NMR, Mass Spectrometry (ESI-MS), and HPLC purity reports, is provided with every batch.

Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical injection, or patient administration without regulatory approval.