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Palmitoyl Pentapeptide-4 (Matrixyl)

  • Palmitoyl Pentapeptide-4
  • CAS number: 214047-00-4
  • Molecular weight: 802.05 g/mol
  • Molecular formula: C39H75N7O10
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Dispersible in water/glycols; Soluble in some organic phases due to the Palmitoyl tail.

    【Product Overview】 We are a specialized global supplier of Palmitoyl Pentapeptide-4, the benchmark "Matrikine" signal peptide famously known by the trade reference Matrixyl. This lipid-soluble peptide is the industry standard for collagen induction therapy in topical formulations. Unlike Acetyl Hexapeptide-8 (which relaxes muscles), Palmitoyl Pentapeptide-4 works by stimulating the skin's fibroblasts to rebuild the extracellular matrix. We provide high-purity, cosmetic-grade powder to formulators creating high-performance anti-aging creams, serums, and eye contour products.

    【Key Advantages】

    Powerful Collagen Synthesis: Acting as a specific messenger peptide (Matrikine), it signals fibroblasts to drastically increase the synthesis of Collagen I, III, and IV, as well as Fibronectin. This structural repair mechanism "fills in" wrinkles from the inside out.

    The "Gentle Retinol" Alternative: Clinical data often compares its efficacy to Retinol in reducing wrinkle depth and roughness, but without the associated skin irritation, peeling, or photosensitivity. It is safe for sensitive skin types.

    Enhanced Bioavailability: The attached Palmitoyl (fatty acid) chain makes the peptide lipophilic. This crucial modification ensures it can penetrate the skin's lipid barrier to reach the deeper dermis, where collagen production occurs.

    Perfect Synergy: It is chemically stable and works synergistically with Acetyl Hexapeptide-8. Combining the two allows brands to claim a "Dual-Action" effect: relaxing dynamic lines while restructuring static wrinkles.

    【Logistics & Service】

    Cosmetic Grade Assurance: Manufactured under strict cGMP guidelines for cosmetic ingredients, ensuring low bio-burden and absence of impurities.

    Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation for your regulatory files.

    Formulation Advice: We can provide guidance on solubility and pH stability (optimal pH 4-7) to ensure successful incorporation into emulsions.

    Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.

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