o-Hydroxybenzoic acid, with a molecular formula of C7H6O3, has a structure of A benzene ring with a hydroxyl group (-OH) in the ortho position (adjacent to) and a carboxylic acid group (-COOH).
It is a β-hydroxy acid extracted from poplar bark, willow bark, etc., and is a simple phenolic compound.
Salicylic acid is known for its anti-inflammatory effects, and also has the effects of regulating keratin, controlling oil, antibacterial, and whitening.
| Test items | Specifications | Test Results | |
| REF | The product is tested in accordance with BP2017/EP9.0/USP42. | ||
| Characters | A white, or almost white , crystalline powder or white or colourless, acicular crystals, slightly soluble in water; freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride. | Complies | |
| Identification | A.Melting pointl58 °C to 161 °C | 158.6-160.5C | |
| B.The IR spectrum of sample complies with Salicylic acid CRS | Complies | ||
| Appearance of solution | Solution is clear and colourless | Clear | |
| Chlorides | <100ppm NMT 100ppm | < 100 ppm | |
| Sulfates | <200ppm NMT 200ppm | <200 ppm | |
| Heavy metals | <20ppm NMT20ppm | <20 ppm | |
| Loss on drying | 50.5%NMT0.5% | 0.02% | |
| Residue on ignition | £0.05%NMT 0.05% | 0.04% | |
| Related substances | 4-hydroxybenzoic acid | M0.1% | 0.001% |
| 4-hydroxyisophthalic acid | £0.05% | 0.002% | |
| Phenol | £0.02% | N.D | |
| Any other impurities | ≤ 0.05% | N.D | |
| Total impurities | ≤ 0.2% | 0.002% | |
| Assay ( on dried basis) | Contains C7H6O3 99.0%-100.5% | 99.6% | |
| Conclusion | The above items meet the requirement. | ||
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