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Lecirelin Acetate – High-Potency Veterinary GnRH

  • Lecirelin Acetate
  • CAS number: 61012-19-9
  • Molecular weight: 1209.42 g/mol
  • Molecular formula: C59H84N16O12
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water and dilute acetic acid

    【Product Overview】 We are a specialized global supplier of Lecirelin Acetate, a synthetic "super-analogue" of Gonadotropin-Releasing Hormone (GnRH). Distinguished by the incorporation of a bulky D-Tert-Leucine (D-Tle) residue at position 6, Lecirelin exhibits exceptional resistance to enzymatic degradation and superior receptor binding affinity compared to native Gonadorelin or Alarelin. We provide this premium API to veterinary pharmaceutical manufacturers and livestock breeding centers, specifically for optimizing reproductive efficiency in dairy cattle and rabbits.

    【Key Advantages】

    Structural Superiority (D-Tle6): The key to Lecirelin’s potency is the unique substitution of Glycine-6 with D-Tert-Leucine. This hydrophobic, bulky amino acid dramatically increases biological stability and half-life, resulting in a stronger and more sustained LH (Luteinizing Hormone) surge.

    Reproductive Management: It is highly effective for the treatment of ovarian follicular cysts, synchronization of estrus (Ovsynch protocols), and prophylaxis of delayed ovulation in cows. In rabbit breeding, it is the standard agent for inducing ovulation post-insemination.

    High Purity Veterinary Grade: We guarantee ≥99.0% purity (HPLC). Our manufacturing process ensures low acetate content and strict control of impurities, meeting the quality standards required for the formulation of veterinary injectables.

    Cost-Effective Potency: Due to its high bio-activity, Lecirelin is effective at lower dosages (microgram levels) compared to first-generation analogues, offering excellent cost-efficiency for large-scale herd management.

    【Technical Specifications】

    Chemical Name: Lecirelin Acetate; [Des-Gly10, D-Tle6, Pro-NHEt9]-GnRH

    CAS Number: 61012-19-9

    Sequence: pGlu-His-Trp-Ser-Tyr-D-Tle-Leu-Arg-Pro-NHEt

    Modification: D-Tert-Leucine at pos 6; Ethylamide at C-terminus.

    Molecular Formula: C59H84N16O12

    Molecular Weight: 1209.42 g/mol

    Appearance: White to off-white lyophilized powder

    Solubility: Soluble in water and dilute acetic acid.

    Storage: Store at -20°C. Protect from light.

    【Logistics & Service】

    Cold Chain Logistics: We utilize insulated packaging with ice packs to ensure the peptide arrives in optimal condition for formulation.

    Export Expertise: We are experienced in the global distribution of veterinary APIs. We provide full HS Code support and necessary non-clinical/veterinary declarations to ensure smooth customs clearance.

    Commercial Scale: Available in flexible quantities, from research grams to bulk 100g+ lots for veterinary drug manufacturing.

    Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for veterinary research and further manufacturing use only. It is NOT intended for human therapeutic use.

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