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Hexamidine Diisethionate
Hexamidine Diisethionate

Hexamidine Diisethionate

  • CAS : 659-40-5
  • Molecular Formula:C20H26N4O2.2C2H6O4S
  • Melting point: 212- 218 °C
  • Purity: ≥ 99.0%
  • H-NMR Spectra Identification: Corresponds
  • OEM ODM Available
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                  Feature

                  Hexamidine Diisethionate salt is a water-soluble cationic substance. It is neutralized by an organic base (hexamidine) and an acid (hydroxyethylsulfonic acid).

                  Specification-COA

                  Tested ItemsSpecificationsResults
                  AppearanceWhite to off-white powderWhite powder
                  IRShould be consistent with that of the reference productComplies
                  Qualitative IdentificationDissolve about 40 mg in 5 mL of water and add dropwise with shaking 1 mL of a 100 g/L solution of sodium chloride. Allow to stand for 5 min. An abundant,shimmering white precipitate is slowly formed.Complies
                  HPLCThe retention time of the main peak of the test solution should be the same as that of the control solutionComplies
                  Loss on drying≤0.3%0.22%
                  Residue on ignition≤0.1%0.02%
                  Purity≥99.0%99.30%
                  Hexamidine content57.5-59.5%58.30%
                  Pb≤10mg/kgND
                  As≤2mg/kgND
                  Hg≤1mg/kgND
                  Cd≤5mg/kgND
                  Total bacterial cfu/g≤200cfu/g<10 cfu/g
                  Molds and Yeast Count,cfu/g≤100cfu/g<10 cfu/g
                  Thermotolerant Coliforms /gNegativeND
                  Staphylococcus aureus /gNegativeND
                  P.Aeruginosa /gNegativeND

                  Function

                  1. It is a new type of anti-dandruff and antipruritic agent due to its unique structure. It has good oil control, anti-irritation and anti-dandruff effects. It can inhibit Malassezia (Pityrosporum ovale) that causes dandruff.
                  2. Highly effective antimicrobial activity, excellent bactericidal and anti-inflammatory properties. In particular, it inhibits acne-causing bacteria (Propionibacterium acnes and Staphylococcus epidermidis) and anaerobic bacteria and fungi associated with acne.
                    It has good bactericidal and antibacterial properties against various Gram-positive and Gram-negative bacteria, as well as various molds and yeasts.

                  Application

                  It is mild and non-irritating, and has the advantages of high-efficiency broad-spectrum antibacterial and bactericidal capabilities, and is widely used in personal care products. It has unique advantages in anti-dandruff, anti-acne and anti-odor formulations.
                  Topical preparations.
                  Preservatives in skin care and personal care products.

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