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Glucagon (Synthetic Human) – Hypoglycemic & Diagnostic API

  • Glucagon
  • CAS number: 16941-32-5
  • Molecular weight: 3482.8 g/mol
  • Molecular formula: C153H225N43O49S
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in dilute acid (pH < 3) or dilute alkali (pH > 9.5)

    【Product Overview】 We are a premier global supplier of Synthetic Human Glucagon, a 29-amino acid polypeptide identical to the natural hormone. Unlike older animal-derived extracts, our product is 100% synthetically manufactured, ensuring an animal-free, pathogen-free profile with high batch-to-batch consistency. It is a critical dual-purpose API: serving as the primary rescue agent for severe hypoglycemia (Anti-Insulin) and as an essential diagnostic aid for inhibiting gastrointestinal motility during radiological examinations.

    【Key Advantages】

    Dual-Market Utility:

    Emergency Care: It stimulates glycogenolysis in the liver, rapidly elevating blood glucose levels. Ideally suited for the development of emergency "Hypoglycemia Rescue Kits."

    Radiology & GI Diagnostics: It temporarily inhibits GI tract motility. This "anti-peristaltic" effect is vital for obtaining clear, artifact-free images during double-contrast radiography, MRI, and CT scans.

    Animal-Free Safety: Our synthetic production route eliminates risks associated with bovine or porcine spongiform encephalopathy (BSE/TSE), meeting the stringent safety requirements of modern regulatory bodies (FDA/EMA).

    High Purity & Activity: We guarantee ≥98.0% purity (HPLC). Our strict synthesis control ensures correct folding and minimizes the formation of fibrils, ensuring the peptide retains maximum biological potency upon reconstitution.

    Commercial Scalability: We offer flexible supply options, from gram-level packs for diagnostic reagent manufacturing to bulk lots for pharmaceutical formulation.

    【Technical Specifications】

    Chemical Name: Glucagon; Human Glucagon (Synthetic)

    CAS Number: 16941-32-5

    Sequence: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH

    Mechanism: Glucagon Receptor Agonist (Glycogenolysis / Smooth Muscle Relaxation)

    Molecular Formula: C153H225N43O49S

    Molecular Weight: 3482.8 g/mol

    Appearance: White to off-white lyophilized powder

    Solubility: Soluble in dilute acid (pH < 3) or dilute alkali (pH > 9.5).

    Storage: Store at -20°C. Protect from light.

    【Logistics & Service】

    Cold Chain Logistics: Glucagon is sensitive to fibrillation. We ship strictly using validated thermal packaging (insulated boxes with dry ice/gel packs) to ensure structural integrity during transit.

    Global Compliance: We are experienced in shipping this critical hormone globally. We provide full HS Code support (2937.19) and necessary non-infectious declarations to facilitate fast customs clearance.

    Technical Support: We provide comprehensive data on pH-dependent solubility, assisting your formulation team in developing stable injectable solutions.

    Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical injection, or patient administration without regulatory approval.

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