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Dihexa (PNB-0408) – Oral Neurogenic API

  • Dihexa (PNB-0408)
  • CAS number: 1401708-83-5
  • Molecular weight: 504.66 g/mol
  • Molecular formula: C27H44N4O5
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in DMSO and Ethanol. (Note: Low solubility in water; requires organic solvent or carrier for liquid formulation)

    【Product Overview】 We are a specialized global supplier of Dihexa (PNB-0408), a synthetic oligopeptide drug candidate and Angiotensin IV analogue. Originally developed by Washington State University, Dihexa is renowned in the neuroscience community for its potent neurogenic activity. It is characterized as a "c-Met agonist" (HGF mimetic) and is distinguished by its ability to cross the blood-brain barrier and its excellent oral bioavailability. We provide high-purity, laboratory-grade Dihexa to research institutions and supplement formulators investigating neurodegenerative diseases and cognitive restoration.

    【Key Advantages】

    Unrivaled Potency: Research indicates that Dihexa is orders of magnitude more potent than Brain-Derived Neurotrophic Factor (BDNF) in promoting synaptogenesis (the creation of new neural connections). It is often cited as one of the most powerful neurogenic compounds currently available in the research market.

    Oral Bioavailability: Unlike most peptide-based nootropics (like Semax or Selank) that require injection or nasal delivery, Dihexa is chemically stable and orally active. This unique property makes it highly attractive for the development of capsule or tablet formulations.

    Blood-Brain Barrier Penetration: Its lipophilic structure allows it to easily penetrate the blood-brain barrier (BBB), ensuring direct action on neuronal receptors.

    High Purity & Stability: We guarantee ≥98.0% purity (HPLC). As an oligopeptide derivative, Dihexa is more stable than long-chain peptides, allowing for easier handling and longer shelf life under proper storage conditions.

    【Logistics & Service】

    Secure Packaging: Dihexa is packed in anti-static, moisture-proof barrier bags or medical-grade vials to prevent contamination.

    Global Export: We are experienced in shipping "Next-Gen Nootropics" to the US, Europe, and Asia. We provide full HS Code support and non-clinical declarations to ensure smooth customs clearance.

    Formulation Support: We can provide technical data regarding solubility profiles to assist your team in developing optimal delivery vehicles (e.g., lipid carriers).Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical consumption, or patient administration without regulatory approval.

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