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Decapeptide-12 – The Tyrosinase Inhibitor (Lumixyl)

  • Decapeptide-12
  • Sequence: Tyr-Arg-Ser-Arg-Lys-Tyr-Ser-Ser-Trp-Tyr
  • Molecular weight: 1395.5 g/mol
  • Molecular formula: C65H90N18O17
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water

    【Product Overview】 We are a specialized global supplier of Decapeptide-12, a potent oligopeptide famously known by the trade reference Lumixyl. Developed by dermatological researchers (originally at Stanford University), this peptide is designed to be a safer, non-irritating alternative to Hydroquinone. It specifically targets and inhibits the Tyrosinase enzyme—the rate-limiting enzyme in melanin production—without the cytotoxicity or side effects associated with traditional chemical lighteners. We provide high-purity powder to formulators creating "Clinical Strength" brightening creams and melasma treatments.

    【Key Advantages】

    Direct Tyrosinase Inhibition: Unlike other peptides that block hormone signals, Decapeptide-12 binds directly to Tyrosinase. In vitro studies suggest it is significantly more potent than Hydroquinone and Kojic Acid in inhibiting enzyme activity, preventing the conversion of Tyrosine to Melanin.

    The "Hydroquinone Killer": It offers the efficacy of prescription-strength lighteners but without the risks of Ochronosis (permanent skin darkening), hypopigmentation (white spots), or skin thinning. It is the gold standard for "Safety + Efficacy."

    Targeting Stubborn Melasma: Due to its high potency, it is particularly effective for treating stubborn Melasma, age spots (Solar Lentigines), and severe photodamage that other milder ingredients cannot shift.

    Non-Cytotoxic: It does not kill melanocytes (pigment cells); it simply puts them to sleep. This ensures that the skin barrier remains intact and healthy during the brightening process.

    【Logistics & Service】

    Cosmetic Grade Quality: Manufactured under strict cGMP guidelines for cosmetic ingredients, ensuring high purity and safety.

    Global Export: We are experienced in shipping cosmetic peptides globally. We provide full HS Code support (typically 2937.19 or 3504.00) and COA/MSDS documentation.

    Formulation Advice: Decapeptide-12 is water-soluble. For maximum stability, avoid formulating with strong oxidizing agents. It works synergistically with Niacinamide and Vitamin C.

    Regulatory Disclaimer: This product is supplied as a Cosmetic Raw Material for further manufacturing and R&D use only. It is intended for topical application and is not for injection.

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