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Cortitorelin Acetate (hCRH) – Corticotropin-Releasing

  • Cortitorelin Acetate (hCRH)
  • CAS number: 86784-85-8
  • Molecular weight: 4757.5 g/mol
  • Molecular formula: C208H344N60O63S2
  • Specifications: 98%
  • Test method:HPLC
  • Solubility: Soluble in water and dilute acetic acid

    【Product Overview】 We are a specialized global supplier of Cortitorelin Acetate, the synthetic form of Human Corticotropin-Releasing Hormone (hCRH). As the primary regulator of the HPA axis, Cortitorelin is the critical upstream signaling peptide used to stimulate ACTH release. We provide this high-value biochemical to research institutions and diagnostic developers for the differential diagnosis of Cushing’s syndrome and the study of stress response mechanisms.

    【Key Advantages】

    HPA Axis Differentiation: Cortitorelin is the gold standard reagent for differentiating between pituitary-dependent (Cushing’s disease) and ectopic ACTH secretion. It acts directly on pituitary corticotrophs, making it an indispensable tool for advanced endocrine research.

    Species Flexibility: We understand that research needs vary. While our standard stock is Human CRH (hCRH) for physiological relevance, we can also supply Ovine CRH (oCRH) upon request, which offers a longer half-life and higher potency for specific experimental models.

    High Purity Assurance: We guarantee ≥98.0% purity (HPLC). Our synthesis platform effectively manages the 41-amino acid sequence, ensuring correct folding and minimizing oxidation of the Methionine residue (Met-21).

    Validated Quality: Each batch undergoes rigorous testing, including Amino Acid Analysis (AAA) and Mass Spectrometry, to confirm peptide content and sequence integrity.

    【Logistics & Service】

    Premium Cold Chain: As a complex 41-amino acid peptide, Cortitorelin is sensitive. We ship using validated thermal packaging (insulated boxes with dry ice/gel packs) to guarantee stability during transit.

    Global Compliance: We are experienced in shipping neurohormones globally. We provide full HS Code support (2937.19) and non-infectious declarations to facilitate fast customs clearance to the US, EU, and Asia.

    Small & Bulk Options: Available in 500mcg and 1mg vials for diagnostic kits, or bulk milligrams for research projects.

    Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical injection, or patient administration without regulatory approval.

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