【Product Overview】 We are a premier global supplier of Buserelin Acetate, a highly potent synthetic analogue of Gonadotropin-Releasing Hormone (GnRH). Engineered with a D-Ser(tBu) substitution at position 6 and an ethylamide modification at the C-terminus, Buserelin offers vastly superior metabolic stability and receptor affinity compared to native Gonadorelin. It is a versatile API widely utilized in both human oncology (prostate cancer management) and veterinary reproduction (equine and bovine fertility).
【Key Advantages】
High Potency & Bioavailability: Buserelin is approximately 20–100 times more potent than natural LHRH. Its unique structure allows for effective absorption via transmucosal routes, making it the preferred API for the development of Nasal Spray formulations, in addition to standard injectables and implants.
Human Health Applications: In the pharmaceutical sector, it is a critical raw material for research into the palliative treatment of advanced prostate carcinoma (testosterone suppression) and the management of endometriosis and IVF protocols (pituitary downregulation).
Veterinary Specialist (Equine & Bovine): Buserelin is extensively used in veterinary medicine, particularly for mares (horses) to induce ovulation and improve conception rates. It is also a staple in dairy herd management for treating ovarian cysts.
High Purity Assurance: We guarantee ≥99.0% purity (HPLC). Our synthesis process strictly controls the D-isomer content and minimizes impurities, ensuring a pharmaceutical-grade product suitable for sensitive reproductive applications.
【Technical Specifications】
Chemical Name: Buserelin Acetate; [D-Ser(tBu)6, Pro-NHEt9]-GnRH
CAS Number: 57982-77-1
Sequence: pGlu-His-Trp-Ser-Tyr-D-Ser(tBu)-Leu-Arg-Pro-NHEt
Mechanism: GnRH Receptor Super-Agonist
Molecular Formula: C60H86N16O13
Molecular Weight: 1239.44 g/mol
Appearance: White to off-white lyophilized powder
Solubility: Soluble in water and dilute acetic acid.
Storage: Store at -20°C. Protect from light.
【Logistics & Service】
Cold Chain Logistics: We utilize validated thermal packaging (insulated boxes with ice packs) to ensure the peptide remains stable during international transit.
Global Compliance: We are experienced in shipping dual-use (human/vet) hormones. We provide full HS Code support (typically 2937.19) and necessary declarations to facilitate smooth customs clearance to the US, EU, and Asia.
Formulation Support: We can provide technical data on stability in aqueous solution to assist in the development of multi-dose vials or nasal sprays.
Regulatory Disclaimer: This product is supplied as a Chemical Reference Standard or API Intermediate for laboratory research (R&D) and further manufacturing use only. It is NOT intended for direct human therapeutic use, clinical injection, or patient administration without regulatory approval.
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