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Azelaic Acid Powder

  • CAS No:123-99-9
  • Appearance:White Powder
  • Specification: 99%
  • MF：C9H16O4
  • MW：188.22
  • Certification:KOSHER,HALAL,ISO.
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                  Feature

                  Azelaic Acid is a straight-chain saturated dicarboxylic acid with 9 carbon atoms in its structure. It is naturally found in plants such as rye, wheat, and barley. Azelaic Acid powder is slightly soluble in cold water and easily soluble in general organic solvents. It is a fat-soluble dibasic acid. It is mainly used in skin care products and pharmaceutical products because of its antibacterial, anti-inflammatory, and oil secretion-inhibiting effects.

                  Specification-COA

                  ItemSpecificationResultTest Methods
                  Assay GC≥98% 99.25%GC
                  Particle Size95% pass 80 meshQualified80 Mesh Screen
                  Loss on drying≤1.0%0.28%5g / 105℃ / 2hrs
                  Residue on Ignition≤0.1%0.08%2g / 525℃ / 3hrs
                  AppearanceFine powderQualifiedVisual
                  Color White or off whiteQualifiedVisual
                  OdorTypicalQualifiedOrganoleptic
                  TasteTypicalQualifiedOlfactory
                  Heavy MetalsNMT10ppm QualifiedICP/MS
                  Arsenic (As)NMT1ppm QualifiedICP/MS
                  Lead (Pb)NMT1ppm QualifiedICP/MS
                  Mercury(Hg)NMT1ppm QualifiedICP/MS
                  Total Plate CountNMT1,000cfu/gQualifiedUSP  
                  Total Yeast & MoldNMT100cfu/gQualifiedUSP
                  E.Coli.NegativeNegativeAOAC
                  SalmonellaNegativeNegativeUSP
                  StaphylococcusNegativeNegativeUSP
                  Packing & StoragePacked in paper-drums and two plastic-bags inside.N.W.:25kgs  Store in a well-closed container Away from moisture.

                  What is the use of azelaic acid powder?

                  1. Antibacterial.
                    Azelaic acid can significantly reduce the number of Propionibacterium acnes in the skin and hair follicles by inhibiting the protein synthesis of Propionibacterium acnes, and has a killing effect on Staphylococcus epidermidis.
                  2. Anti-inflammatory effect.
                    Azelaic acid can inhibit the production of reactive oxygen free radicals and exert anti-inflammatory effects. In addition, azelaic acid can reduce the inflammatory cascade of cytokine interleukin-1β (IL-1β) by inhibiting nuclear transcription factor (NFκB).
                  3. Regulate keratinization of hair follicles.
                    Azelaic acid can reduce the synthesis of filamentous keratin and prevent excessive keratinization of hair follicles.
                  4. Inhibit oil secretion.
                    It can improve excessive oil secretion of the skin caused by androgen.
                  5. Whitening and reducing pigmentation.
                    Azelaic acid exerts a whitening effect by inhibiting the activity of tyrosinase, especially in reducing pigmentation. In addition, it can also hinder the proliferation of abnormal melanocytes.

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